Saskatchewan IG Stewardship Program
Intravenous immunoglobulin (IVIG) and subcutaneous immunoglobulin (SCIG) are costly and limited-supply blood products. Judicious use of IG therapy is important to ensure a continued supply is available for patients in need.
The Saskatchewan IG Stewardship Program was initiated to monitor and ensure appropriate use of IVIG. The program incorporates the tri-provincial guideline ‘Criteria for the Clinical Use of Immune Globulin’ (Second Edition February 2022) which requires screening of IVIG requests by program and laboratory staff to ensure IG is used in accordance with the guideline’s recommended clinical indications and dosages. Regina and Saskatoon Transfusion Medicine Physicians support provincial screening of select conditions.
The Saskatchewan IG Stewardship Program has led to more appropriate IVIG use across the province and has effectively supported national preservation of this limited healthcare resource.
Contact:
IG Nurse Navigators
Phone: 306-766-3135
Fax: 306-766-3509
Email: igstewardshipprogram@saskhealthauthority.ca
Regular Hours:
Monday-Friday, 8:00 am to 4:30 pm excluding statutory holidays
For urgent requests, please contact your local Transfusion Medicine laboratory for assistance
TML Screening Oders Education
Frequently Asked Questions (FAQ's)
Provincial IG Order Sets
- SHA CS-OS-1910 Adult 10% Intravenous Immune Globulin (IVIG) Order Set
- SHA CS-OS-1911 Infant and Pediatric Intravenous Immune Globulin Order Set
- CS-OS-1913 NICU Intravenous Immune Globulin Order Set
- SHA CS-OS-1912 Measles Post-Exposure Prophylaxis (PEP) – Intravenous Immune Globulin (IVIG) Order Set for Emergency Department Use Only
SHA Blood Products: Monographs & Resources
- Intravenous Immunoglobulin, 10%
- Intravenous Immunoglobulin Solvent Detergent Treated, 5%
- Subcutaneous Immunoglobulin, 20%
- Subcutaneous Immunoglobulin, 10% with Hyaluronidase
Please refer to the applicable blood product monograph for detailed clinical and administration information.
SHA Patient Information and Education (PIER) Resources for IG:
- Intravenous Immune Globulin – Adult – Information for Patients and Families Brochure (CS-PIER-0010)
- Intravenous Immune Globulin – Pediatrics – Information for Patients and Families Brochure (CS-PIER-0011)
- Intravenous Immune Globulin Patient Logbook (CS-PIER-0005)
- Immune Globulin – Frequently Asked Questions (CS-PIER-0006)
- Immune Globulin Therapy Options – Which IG Therapy is Best for Me? (CS-PIER-0009)
- Subcutaneous Immune Globulin – Information for Patients and Families (CS-PIER-0008)
Simulation Exercise
Job Aides, Posters and Work Standards
| Document Name | Date of Original Publication | Date Revised |
|---|
| Poster - TML Selection 10 % IVIG Vials for NICU/Infant/Pediatric Patients | September 23, 2024 | June 11, 2026 | Download |
| TML Screening of INFANT/PEDIATRIC Order Sets | June 17, 2026 | June 17, 2026 | Download |
| TML Screening of NICU Order Sets | June 17, 2026 | June 17, 2026 | Download |
| WS - TML Screening of Inpatient and Urgent Outpatient ADULT 10% IVIG Order Sets | August 29, 2024 | April 17, 2026 | Download |
Memos
| Document Name | Date of Original Publication | Date Revised |
|---|
| Sharing of Patient Information to Monitor the SHA Immune Globulin (IG) Stewardship Program (Program) | January 20, 2026 | January 20, 2026 | Download |
| Safe Practices for TML Screening of ADULT and PEDIATRIC 10% Intravenous Immune Globulin Order Set Doses | August 29, 2024 | August 29, 2024 | Download |
| Revised Adult 10% Intravenous Immune Globulin (IVIG) Provincial Order Set CS-OS-1910 | March 21, 2025 | March 21, 2025 | Download |
| New Measles Post-Exposure Prophylaxis - Intravenous Immune Globulin (IVIG) Order Set Now | August 29, 2024 | August 29, 2024 | Download |
Links
- CADTH: Off-Label Use of Intravenous Immunoglobulin (IVIG)
- CBS: Professional Education/Transfusion: Exploring the frontiers of IVIG-associated hemolysis
- Immunodeficiency Canada Network
- NAC: Immunoglobulin Utilization Statement
- NAC: Intravenous Immunoglobulin (IVIg) Brand Switching Guidance and Resources
- NAC: The National Plan for Management of Shortages of Immunoglobulin (lg) Products
Programs
What’s Popular
- About Us
- IVIG Dose Calculator – Based on Adjusted Body Weight
- Prenatal Testing and Prevention of Alloimmunization in Mothers of Saskatchewan (PRAMS) Program
- Saskatchewan Immune Globulin Stewardship Program
- Saskatchewan Transfusion Adverse Event Report Form (SHA 0481)
- Transfusion Best Practice Recommendations
- Transfuse Wisely Poster
- Using Blood Wisely – Intervention Toolbox
- Visual Inspection Tool – Canadian Blood Services
Useful Links
- Canadian Agency for Drugs and Technologies in Health (CADTH)
- Canadian Blood Services
- Canadian Blood Services Professional Education
- Canadian Immunodeficiencies Patient Organization
- Canadian Society for Transfusion Medicine (CSTM)
- Choosing Wisely Canada
- HAE Canada Website
- Jehovah’s Witnesses
- National Advisory Committee on Blood and Blood Products
- ONTraC – Ontario Transfusion Coordinators
- ORBCoN – Ontario Regional Blood Coordinating Network
- REDCap
- Saskatchewan Bleeding Disorder Program
- SaskBlood SharePoint
- Society for the Advancement of Blood Management (SABM)
- Treat the Bleed