Fibrinogen Concentrates
Fibrinogen concentrate (FC) is concentrated fibrinogen derived from pooled human plasma which is available as a lyophilized powder requiring reconstitution before administration. Fibrinogen concentrates have a superior safety profile as a pathogen inactivated product, and logistical advantages with respect to dosing, storage and administration. There are two FC products currently available in Canada: RiaSTAP (CSL Behring) and Fibryga (Octapharma).
Resources
| Document Name | Date of Original Publication | Date Revised |
|---|
| Fibryga Reconstitution Instructions, CSL Behring | September 6, 2024 | September 6, 2024 | Download |
| RiaSTAP Step-by-Step One Page Reconstitution Guide, Octapharma | September 6, 2024 | September 6, 2024 | Download |
| RQHR PPO #627 - Ordering of Human Fibrinogen Concentrate (RiaSTAP™) | June 21, 2018 | October 10, 2025 | Download |
Links
- Blood Bank Contact and Stock Information – Saskatchewan
- SHA Blood Products: Monographs & Resources – Fibryga
- SHA Blood Products: Monographs & Resources – RiaSTAP
- Fibryga: Human Fibrinogen Concentrate – fibrygaresources.ca
- Fibryga Virtual Tool Kit – Octapharma
- RiaSTAP: Administration Step-by-Step Guide – CSL Behring
- RiaSTAP: CSL Behring Healthcare Professional Hub
- RiaSTAP: Fibrinogen Concentrate (Human) Fact Sheet
- NAC Statement on Fibrinogen Concentrate Use in Acquired Hypofibrinogenemia
- Transfusion Best Practice Recommendations Saskatchewan
Blood Products
What’s Popular
- About Us
- IVIG Dose Calculator – Based on Adjusted Body Weight
- Prenatal Testing and Prevention of Alloimmunization in Mothers of Saskatchewan (PRAMS) Program
- Saskatchewan Immune Globulin Stewardship Program
- Saskatchewan Transfusion Adverse Event Report Form (SHA 0481)
- Transfusion Best Practice Recommendations
- Transfuse Wisely Poster
- Using Blood Wisely – Intervention Toolbox
- Visual Inspection Tool – Canadian Blood Services
Useful Links
- Canadian Agency for Drugs and Technologies in Health (CADTH)
- Canadian Blood Services
- Canadian Blood Services Professional Education
- Canadian Immunodeficiencies Patient Organization
- Canadian Society for Transfusion Medicine (CSTM)
- Choosing Wisely Canada
- HAE Canada Website
- Jehovah’s Witnesses
- National Advisory Committee on Blood and Blood Products
- ONTraC – Ontario Transfusion Coordinators
- ORBCoN – Ontario Regional Blood Coordinating Network
- REDCap
- Saskatchewan Bleeding Disorder Program
- SaskBlood SharePoint
- Society for the Advancement of Blood Management (SABM)
- Treat the Bleed