Prenatal Testing and Prevention of Alloimmunization in Mothers of Saskatchewan (PRAMS) Program


In expectant mothers, it is standard of care for maternal blood group with Rh determination and antibody screen testing (ABO/Rh type and Ab Screen) to be performed to evaluate for fetal risk of hemolytic disease of the fetus and newborn (HDFN). Current clinical practice guidelines recommend that all expectant patients be typed and undergo a screen for alloantibodies at their first prenatal visit, with results of initial testing guiding the need for further investigations.

Prenatal transfusion medicine testing (ABO/Rh Type and Ab Screen) is currently provided to residents of Saskatchewan through Canadian Blood Services (CBS) in Vancouver.  This testing will transition to the Laboratories of the Saskatchewan Health Authority on February 3, 2020.  This allows us to provide care closer to home for our patients, improving the turn-around time and the information flow of test results electronically. These changes will impact your practice and improve the delivery of care for your patients.

Transmissible disease ordering and testing processes will remain unchanged.

Prenatal Transfusion Medicine Testing changes effective February 3, 2020

Facts you need to know:

  1. Test results will be available in e-Health and EMRs, as opposed to the current experience of receiving paper faxes from CBS.
  2. A new requisition will be in use effective February 3, 2020 titled Saskatchewan Health Authority, Prenatal Request for Testing. The new requisition will be pushed out to Accuro users and will be available for download from MedAccess in late January. Paper-based offices may access the new requisition under the FORMS section below.
  3. Antibody titer reporting will change. SHA laboratories use automated testing for antibody titers, which is considerably more sensitive than manual testing methods used by CBS. This will impact titer interpretation and the identification of critical thresholds for patients. The new critical threshold for referral to specialist care will be 64, rather than 16.
  4. Free webinars are available to support learning about these testing changes and how it will impact your practice and improve the delivery of care for your patients.
Webinar Information
Join a free educational WebEx to learn more:
Date  Time WebEx Link
(Preferred Method)
Join by Phone Toll Free
January 21, 2020 1200-1230 Join January 21 WebEx Meeting Number: 798 763 364
January 22, 2020 0715-0745 Join January 22 WebEx Meeting Number: 797 892 532
January 23, 2020 1630-1700 Join January 23 WebEx Meeting Number: 790 835 625
January 27, 2020 1200-1230 Join January 27 WebEx Meeting Number: 799 603 400
January 29, 2020 1230-1300 Join January 29 WebEx Meeting Number: 798 191 398
January 30, 2020 1300-1330 Join January 30 WebEx Meeting Number: 797 230 858

Test Centers

Routine Testing
Transfusion Medicine Laboratory
Regina General Hospital
1440 – 14th Ave.
Regina, SK S4P 0W5
Phone: 306-766-4474
Fax: 306-766-4004
Transfusion Medicine Laboratory
Victoria Hospital
1200 24th St. West
Prince Albert, SK S6V 4B2
Phone: 306-765-6146
Fax: 306-765-6163
Transfusion Medicine Laboratory
St. Paul’s Hospital
1702 20th St. West
Saskatoon, SK S7M 0Z9
Phone: 306-655-5168
Fax: 306-655-5101
Serving former Health Regions of:
Cypress, Five Hills, Regina Qu’Appelle, Sun Country, Sunrise Athabasca, Kelsey Trail, Prince Albert Parkland, Mamawetan Heartland, Keewatin, Prairie North, Saskatoon
Provincial Reference Testing

Transfusion Medicine Laboratory
Royal University Hospital
Room G502, 103 Hospital Dr.
Saskatoon, SK S7N 0W8
Phone: 306-655-2179
Fax: 306-655-2222


Document Name Date of Original Publication Date Revised  


    Document Name Date of Original Publication Date Revised  
    Request for Prenatal Testing January 8, 2020 January 10, 2020 Download


      Titer Intepretations
      Document Name Date of Original Publication Date Revised  


        Contact Information

        For questions, please contact:

        Kalen Paulson, PRAMS Provincial Project Manager, Laboratory Medicine at or 306-514-7072.

        Links of Interest